Concepedia

PK-Sim®: a physiologically based pharmacokinetic ‘whole-body’ model

Stefan Willmann, Jörg Lippert, Michael Sevestre, Juri Solodenko, F. Fois, Walter Schmitt

BIOSILICO · 2003 · 214 citations · 6 references

DOI

Concepts

References

6

Principles and Methods of Toxicology

Food and Chemical Toxicology · 1984 · 1.4K citations

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A Priori Prediction of Tissue:Plasma Partition Coefficients of Drugs to Facilitate the Use of Physiologically‐Based Pharmacokinetic Models in Drug Discovery

Patrick Poulin, Frank‐Peter Theil · Journal of Pharmaceutical Sciences · 2000 · 423 citations

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Principles and methods of toxicology

H.C. Krebs · Toxicon · 1995 · 327 citations

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Prediction of Pharmacokinetics Prior to In Vivo Studies. II. Generic Physiologically Based Pharmacokinetic Models of Drug Disposition

Patrick Poulin, Frank‐Peter Theil · Journal of Pharmaceutical Sciences · 2002 · 300 citations

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Physiologically based pharmacokinetic study on a cyclosporin derivative, SDZ IMM 125

Ryosei Kawai, Michel Lemaire, Jean‐Louis Steimer et al. · Journal of Pharmacokinetics and Biopharmaceutics · 1994 · 144 citations

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