Michael Sevestre

Development of a Physiology-Based Whole-Body Population Model for Assessing the Influence of Individual Variability on the Pharmacokinetics of Drugs

Stefan Willmann, Karsten Höhn, Andrea N. Edginton et al. · Journal of Pharmacokinetics and Pharmacodynamics · 2007 · 241 citations

Pharmacokinetic Modeling, Pharmacodynamics, Individual Variability +4

PK-Sim®: a physiologically based pharmacokinetic ‘whole-body’ model

Stefan Willmann, Jörg Lippert, Michael Sevestre et al. · BIOSILICO · 2003 · 203 citations

Pharmacokinetic Modeling, Medicine, Physiology +3

Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models

M. Vossen, Michael Sevestre, Christoph Niederalt et al. · Theoretical Biology and Medical Modelling · 2007 · 63 citations · Full text

Physiologically Based Pharmacokinetic Approach to Determine Dosing on Extracorporeal Life Support: Fluconazole in Children on<scp>ECMO</scp>

Kevin Watt, Michael Cohen‐Wolkowiez, Jeffrey S. Barrett et al. · CPT Pharmacometrics & Systems Pharmacology · 2018 · 48 citations · Full text

The Integration of Allometry and Virtual Populations to Predict Clearance and Clearance Variability in Pediatric Populations over the Age of 6 Years

Andrea N. Edginton, Bhavank Shah, Michael Sevestre et al. · Clinical Pharmacokinetics · 2013 · 46 citations

Virtual Populations, Population Children, Child Health +8