Jean‐Louis Steimer

Alternative Approaches to Estimation of Population Pharmacokinetic Parameters: Comparison with the Nonlinear Mixed-Effect Model

Jean‐Louis Steimer, Alain Mallet, Jean‐Louis Golmard et al. · Drug Metabolism Reviews · 1984 · 277 citations

Modelling Response Time Profiles in the Absence of Drug Concentrations: Definition and Performance Evaluation of the K–PD Model

Philippe Jacqmin, Eric Snoeck, E.A. van Schaick et al. · Journal of Pharmacokinetics and Pharmacodynamics · 2006 · 160 citations

Systems Pharmacology, Therapeutic Drug Monitoring, Pharmacokinetic Modeling +14

Physiologically based pharmacokinetic study on a cyclosporin derivative, SDZ IMM 125

Ryosei Kawai, Michel Lemaire, Jean‐Louis Steimer et al. · Journal of Pharmacokinetics and Biopharmaceutics · 1994 · 143 citations

Therapeutic Drug Monitoring, Physiology, Pharmacology +8

An Evaluation of the Integration of Pharmacokinetic and Pharmacodynamic Principles in Clinical Drug Development

Bruno Reigner, Peter Williams, Indra H. Patel et al. · Clinical Pharmacokinetics · 1997 · 119 citations

Pharmacological Study, Pharmacodynamics, Drug Discovery +5

Relationships Between Exposure to Saquinavir Monotherapy and Antiviral Response in HIV-Positive Patients

Ronald Gieschke, B. Fotteler, Neil Buss et al. · Clinical Pharmacokinetics · 1999 · 99 citations

Treatment And Prevention, Antiviral Response, Antiviral Therapy +7