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Modelling Response Time Profiles in the Absence of Drug Concentrations: Definition and Performance Evaluation of the K–PD Model

Systems PharmacologyTherapeutic Drug MonitoringPharmacokinetic ModelingK–pd ModelMedicineQuantitative PharmacologyTime-varying ConfoundingDrug MonitoringSystem PharmacologyDrug AssessmentPharmacologyPhysiologically-based Pharmacokinetic ModelingStatisticsPharmacokineticsPharmacodynamic ModelingResponse Time ProfilesDrug Analysis