Concepedia

Synthesis and evaluation of azapeptide-derived inhibitors of serine and cysteine proteases

Todd L. Graybill, Mitchell J. Ross, Bruce R. Gauvin, Jill S. Gregory, Alex L. Harris, Mark A. Ator, James M. Rinker, Roland E. Dolle

Bioorganic & Medicinal Chemistry Letters · 1992 · 56 citations · 9 references

DOI

Concepts

References

9

Azapeptides

Joachim Gante · Synthesis · 1989 · 168 citations

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Peptidyl (acyloxy)methyl ketones and the quiescent affinity label concept: the departing group as a variable structural element in the design of inactivators of cysteine proteinases

Allen Krantz, Leslie J. Copp, Peter J. Coles et al. · Biochemistry · 1991 · 143 citations

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Synthesis of peptide fluoromethyl ketones and the inhibition of human cathepsin B

David Rasnick · Analytical Biochemistry · 1985 · 126 citations

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Polypeptides. Part XIII. Preparation of α-aza-amino-acid (carbazic acid) derivatives and intermediates for the preparation of α-aza-peptides

Anand S. Dutta, John S. Morley · Journal of the Chemical Society Perkin Transactions 1 · 1975 · 88 citations

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Reaction of azapeptides with chymotrypsin-like enzymes. New inhibitors and active site titrants for chymotrypsin A alpha, subtilisin BPN', subtilisin Carlsberg, and human leukocyte cathepsin G.

B. Frank Gupton, David Carroll, Peter M. Tuhy et al. · Journal of Biological Chemistry · 1984 · 70 citations · Full text

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