Synthesis of peptide fluoromethyl ketones and the inhibition of human cathepsin B

Methods in Enzymology , Vol

S P Colowick, M D Joshi, Jagannathan et al. · 1966 · 26.2K citations

Life Sciences, Biochemistry, Molecular Biology +10

Esters of Methanesulfonic Acid as Irreversible Inhibitors of Acetylcholinesterase

Richard J. Kitz, Irwin B. Wilson · Journal of Biological Chemistry · 1962 · 1.5K citations · Full text

Life Sciences, Biochemistry, Pharmacology +13

L-<i>trans</i>-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L

A. John Barrett, A A Kembhavi, M A Brown et al. · Biochemical Journal · 1982 · 1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

<i>N,N</i>‐Dimethyl‐4‐pyridinamine, a Very Effective Acylation Catalyst

Wölfgang Steglich, Gerhard Höfle · Angewandte Chemie International Edition in English · 1969 · 527 citations

Natural Sciences, Chemical Engineering, Chemistry +11

Specificity of porcine pancreatic elastase, human leukocyte elastase and cathepsin G Inhibition with peptide chloromethyl ketones

James C. Powers, B. Frank Gupton, A. Dale Harley et al. · Biochimica et Biophysica Acta (BBA) - Enzymology · 1977 · 223 citations

Life Sciences, Biochemistry, Immunology +15