Concepedia

A High-Fat Diet and NAD + Activate Sirt1 to Rescue Premature Aging in Cockayne Syndrome

Morten Scheibye‐Knudsen, Sarah J. Mitchell, Evandro Fei Fang, Teruaki Iyama, Theresa M. Ward, James Wang, Christopher Dunn, N. Singh, Sebastian Veith, Md Mahdi Hasan‐Olive,

Cell Metabolism · 2014 · 354 citations · 22 references

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22

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik et al. · Nature · 2013 · 4K citations · Full text

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A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

Pere Puigserver, Zhidan Wu, Cheol Won Park et al. · Cell · 1998 · 3.8K citations · Full text

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Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

Tadahiro Shimazu, Matthew D. Hirschey, Wenjuan He et al. · Science · 2012 · 1.7K citations · Full text

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Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging

Ana P. Gomes, Nathan L. Price, Alvin J. Y. Ling et al. · Cell · 2013 · 1.5K citations · Full text

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The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

Laurent Mouchiroud, Riekelt H. Houtkooper, Norman Moullan et al. · Cell · 2013 · 1.2K citations · Full text

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