Concepedia

Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

Daming Gao, Hiroyuki Inuzuka, Alan Tseng, Y. Rebecca Chin, Alex Toker, Wenyi Wei

Nature Cell Biology · 2009 · 279 citations · 40 references

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References

40

Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor

Anne Brunet, Azad Bonni, Michael J. Zigmond et al. · Cell · 1999 · 6.6K citations · Full text

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Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

Sandeep Robert Datta, Henryk Dudek, Xu Tao et al. · Cell · 1997 · 5.7K citations · Full text

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SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

Andrea C. Carrano, Esther Eytan, Avram Hershko et al. · Nature Cell Biology · 1999 · 1.5K citations

, , +12

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

Binhua P. Zhou, Yong Liao, Weiya Xia et al. · Nature Cell Biology · 2001 · 1.2K citations

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PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

Jiyong Liang, Judit Zubovitz, Teresa Petrocelli et al. · Nature Medicine · 2002 · 945 citations

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