Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

Sandeep Robert Datta, Henryk Dudek, Xu Tao, +4

Cell

Signal TransductionSignaling PathwayCell RegulationAkt PhosphorylationApoptosis +9

Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt

Henryk Dudek, Sandeep Robert Datta, Thomas Franke, +6

Science

Calcium Influx via the NMDA Receptor Induces Immediate Early Gene Transcription by a MAP Kinase/ERK-Dependent Mechanism

Zhengui Xia, Henryk Dudek, Cindy K. Miranti, +1

Journal of Neuroscience

Cellular NeurobiologyGlutamate SignalsCellular PhysiologyTranscriptional RegulationCalcium Influx +17

Sonic Hedgehog Is Required for Progenitor Cell Maintenance in Telencephalic Stem Cell Niches

Robert Machold, Shigemi Hayashi, Michael Rutlin, +9

Neuron

BiologyEmbryonic Stem CellCell LineageDevelopmental BiologyMedicine +9

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation.

Margareta Nikolić, Henryk Dudek, Young T. Kwon, +2

Genes & Development

Neuronal DifferentiationCytoskeletonCellular NeurobiologySynaptic SignalingCellular Physiology +19

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

Maria Frank-Kamenetsky, Xiaoyan M. Zhang, Steve Bottega, +9

Journal of Biology

Serine 133-Phosphorylated CREB Induces Transcription via a Cooperative Mechanism That May Confer Specificity to Neurotrophin Signals

Azad Bonni, David D. Ginty, Henryk Dudek, +1

Molecular and Cellular Neuroscience

NeurotransmitterNeurotransmissionMay Confer SpecificitySocial SciencesTranscriptional Regulation +18

N-methyl-d-aspartate receptors are critical for mediating the effects of glutamate on intracellular calcium concentration and immediate early gene expression in cultured hippocampal neurons

Hilmar Bading, Michael M. Segal, Nikolaus J. Sucher, +3

Neuroscience

Synaptic PlasticityEarly Gene ExpressionSynaptic SignalingNeurophysiologyPhysiology +8

Myb and Ets proteins cooperate in transcriptional activation of the mim-1 promoter.

Henryk Dudek, Ramana Tantravahi, V. N. Rao, +2

Proceedings of the National Academy of Sciences

Molecular RegulationGeneticsMim-1 PromoterGene Regulatory NetworkEts Genes +17

Specific Inhibition of Hepatic Lactate Dehydrogenase Reduces Oxalate Production in Mouse Models of Primary Hyperoxaluria

Cheng-Jung Lai, Natalie W. Pursell, Jessica J. Gierut, +15

Molecular Therapy