Young T. Kwon

Neurotoxicity induces cleavage of p35 to p25 by calpain

Ming‐Sum Lee, Young T. Kwon, Mingwei Li et al. · Nature · 2000 · 1.1K citations

Biochemistry, Medicine, Neuropharmacology +4

Mice Lacking p35, a Neuronal Specific Activator of Cdk5, Display Cortical Lamination Defects, Seizures, and Adult Lethality

Teresa H. Chae, Young T. Kwon, Roderick T. Bronson et al. · Neuron · 1997 · 726 citations · Full text

Knockout Mouse, Molecular Neuroscience, Developmental Biology +12

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation.

Margareta Nikolić, Henryk Dudek, Young T. Kwon et al. · Genes & Development · 1996 · 595 citations · Full text

Neuronal Differentiation, Cytoskeleton, Cellular Neurobiology +21

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

James Bibb, Gretchen L. Snyder, Akinori Nishi et al. · Nature · 1999 · 559 citations

Signal Transduction, Molecular Neuroscience, Medicine +11

A Structural Basis for Substrate Specificities of Protein Ser/Thr Kinases: Primary Sequence Preference of Casein Kinases I and II, NIMA, Phosphorylase Kinase, Calmodulin-Dependent Kinase II, CDK5, and Erk1

Zhou Songyang, Kun Ping Lu, Young T. Kwon et al. · Molecular and Cellular Biology · 1996 · 550 citations · Full text

Molecular Biology, Protein Kinase A, Signaling Pathway +20