High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

Jordi Folch, Marjorie B. Lees, G H S Stanley · Journal of Biological Chemistry · 1957 · 64.9K citations · Full text

Life Sciences, Biochemistry, Bioseparations +11

Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

Salvatore Oddo, Antonella Caccamo, Jason D. Shepherd et al. · Neuron · 2003 · 4.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +12

Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis

Rakez Kayed, Elizabeth Head, Jennifer L. Thompson et al. · Science · 2003 · 4.1K citations

Life Sciences, Biochemistry, Neuroscience +17

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

Paulina V. Arriagada, John H. Growdon, E. Tessa Hedley‐Whyte et al. · Neurology · 1992 · 2.7K citations

Medicine, Neurology, Neuroscience +16

Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

Donalyn Scheuner, Christopher B. Eckman, M. Jensen et al. · Nature Medicine · 1996 · 2.6K citations

Life Sciences, Neurobiology, Neuroscience +16