Concepedia

Mincle is an ITAM-coupled activating receptor that senses damaged cells

Sho Yamasaki, Eri Ishikawa, Machie Sakuma, Hiromitsu Hara, Koji Ogata, Takashi Saito

Nature Immunology · 2008 · 738 citations · 46 references

DOI

Concepts

References

46

Gout-associated uric acid crystals activate the NALP3 inflammasome

Fabio Martinon, Virginie Pétrilli, Annick Mayor et al. · Nature · 2006 · 5.2K citations

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Molecular identification of a danger signal that alerts the immune system to dying cells

Yan Shi, Kenneth L. Rock · Nature · 2003 · 1.7K citations

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Apaf1 Is Required for Mitochondrial Pathways of Apoptosis and Brain Development

Hiroki Yoshida, Young‐Yun Kong, Ritsuko Yoshida et al. · Cell · 1998 · 1.1K citations · Full text

, , +14

C1q and Mannose Binding Lectin Engagement of Cell Surface Calreticulin and Cd91 Initiates Macropinocytosis and Uptake of Apoptotic Cells

Carol Anne Ogden, Aimee M. deCathelineau, Peter Hoffmann et al. · The Journal of Experimental Medicine · 2001 · 1.1K citations · Full text

, , +13

Syk-Dependent Cytokine Induction by Dectin-1 Reveals a Novel Pattern Recognition Pathway for C Type Lectins

Neil C. Rogers, Emma Slack, Alexander D. Edwards et al. · Immunity · 2005 · 881 citations · Full text

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