Concepedia

Machie Sakuma

MS

15

Publications

2.1K

Citations

13

H-Index

1997

Active since

Affiliations

RIKEN Center for Integrative Medical Sciences(Current)

The University of Osaka

Chiba University

Kazusa DNA Research Institute

Hospital for Sick Children

Machie Sakuma is an author at RIKEN Center for Integrative Medical Sciences specializing in medicine, signal transduction, and immunology.

Top concepts

MedicineSignal TransductionImmunologyCell BiologyCell SignalingCell PhysiologyAutoimmunitySystems BiologyT Cell ImmunityImmune Regulation

Publications per year

1997–2019

15

Publications

15

Mincle is an ITAM-coupled activating receptor that senses damaged cells

Sho Yamasaki, Eri Ishikawa, Machie Sakuma et al. · Nature Immunology · 2008 · 726 citations

Molecular Physiology, Signal Transduction, Itam-coupled Activating Receptor +9

C-type lectin Mincle is an activating receptor for pathogenic fungus, <i>Malassezia</i>

Sho Yamasaki, Makoto Matsumoto, Osamu Takeuchi et al. · Proceedings of the National Academy of Sciences · 2009 · 417 citations · Full text

Regulation of Cell Surface Expression of CTLA-4 by Secretion of CTLA-4-Containing Lysosomes Upon Activation of CD4+ T Cells

Tomohiko Iida, Hiroshi Ohno, Chiaki Nakaseko et al. · The Journal of Immunology · 2000 · 179 citations · Full text

Immunology, Immune Regulation, Molecular Biology +22

Dynein-Driven Transport of T Cell Receptor Microclusters Regulates Immune Synapse Formation and T Cell Activation

Akiko Hashimoto, Tadashi Yokosuka, Kumiko Sakata-Sogawa et al. · Immunity · 2011 · 163 citations · Full text

T Cell Activation, Signal Transduction, Cell Interaction +11

Mechanistic basis of pre–T cell receptor–mediated autonomous signaling critical for thymocyte development

Sho Yamasaki, Eri Ishikawa, Machie Sakuma et al. · Nature Immunology · 2005 · 152 citations

Signal Transduction, Developmental Biology, Lymphocyte Development +14

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