Concepedia

NMS-P937, a 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivative as potent and selective Polo-like kinase 1 inhibitor

Italo Beria, R Bossi, Maria Gabriella Brasca, Michele Caruso, Walter Ceccarelli, Gabriele Fachin, Marina Fasolini, Barbara Forte, Francesco Fiorentini, Enrico Pesenti,

Bioorganic & Medicinal Chemistry Letters · 2011 · 104 citations · 10 references

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10

Physicochemical High Throughput Screening:  Parallel Artificial Membrane Permeation Assay in the Description of Passive Absorption Processes

Manfred Kansy, Frank Senner, Klaus Gubernator · Journal of Medicinal Chemistry · 1998 · 1.3K citations

, , +16

The polo‐like protein kinases Fnk and Snk associate with a Ca2+‐ and integrin‐binding protein and are regulated dynamically with synaptic plasticity

Gunther Kauselmann · The EMBO Journal · 1999 · 206 citations · Full text

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Polo-like Kinase-1 Is Required for Bipolar Spindle Formation but Is Dispensable for Anaphase Promoting Complex/Cdc20 Activation and Initiation of Cytokinesis

Marcel A.T.M. van Vugt, Barbara C. M. van de Weerdt, Gerben Vader et al. · Journal of Biological Chemistry · 2004 · 203 citations · Full text

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Use of the Novel Plk1 Inhibitor ZK-Thiazolidinone to Elucidate Functions of Plk1 in Early and Late Stages of Mitosis

Anna Santamaría, Rüdiger Neef, Uwe Eberspächer et al. · Molecular Biology of the Cell · 2007 · 198 citations

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Polo‐like kinase 1 is overexpressed in prostate cancer and linked to higher tumor grades

Wilko Weichert, Mathias Schmidt, Volker Gekeler et al. · The Prostate · 2004 · 189 citations

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