Maria Gabriella Brasca

3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 1. Lead Finding

Paolo Pevarello, Maria Gabriella Brasca, Raffaella Amici et al. · Journal of Medicinal Chemistry · 2004 · 157 citations · Full text

Drug Target, Lead Identification, Pharmacotherapy +23

Identification of <i>N</i>,1,4,4-Tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1<i>H</i>-pyrazolo[4,3-<i>h</i>]quinazoline-3-carboxamide (PHA-848125), a Potent, Orally Available Cyclin Dependent Kinase Inhibitor

Maria Gabriella Brasca, Nadia Amboldi, Dario Ballinari et al. · Journal of Medicinal Chemistry · 2009 · 125 citations · Full text

Drug Target, Chemoprevention Strategy, Gynecology +18

3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 2. Lead Optimization

Paolo Pevarello, Maria Gabriella Brasca, Paolo Orsini et al. · Journal of Medicinal Chemistry · 2005 · 107 citations · Full text

Chemoprevention Strategy, Pharmacotherapy, Chemical Biology +20

NMS-P937, a 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivative as potent and selective Polo-like kinase 1 inhibitor

Italo Beria, R Bossi, Maria Gabriella Brasca et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 104 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +9

A highly convergent total synthesis of the spiroacetal macrolide (+)-milbemycinβ1

Steven V. Ley, Neville J. Anthony, Alan Armstrong et al. · Tetrahedron · 1989 · 93 citations

Pharmacology, Synthetic Chemistry, Biomolecular Engineering +2