R Bossi

Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

Maria Menichincheri, Elena Ardini, Paola Magnaghi et al. · Journal of Medicinal Chemistry · 2016 · 298 citations · Full text

Medicine, Oncology, Pharmacology +17

Targeting the Mitotic Checkpoint for Cancer Therapy with NMS-P715, an Inhibitor of MPS1 Kinase

Riccardo Colombo, Marina Caldarelli, Milena Mennecozzi et al. · Cancer Research · 2010 · 201 citations · Full text

Medicine, Cancer Biology, Oncology +17

Crystal Structures of Anaplastic Lymphoma Kinase in Complex with ATP Competitive Inhibitors

R Bossi, Maria Beatrice Saccardo, Elena Ardini et al. · Biochemistry · 2010 · 167 citations

Life Sciences, Molecular Biology, Oncology +17

NMS-P937, a 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivative as potent and selective Polo-like kinase 1 inhibitor

Italo Beria, R Bossi, Maria Gabriella Brasca et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 104 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

Cross-Talk and Ammonia Channeling between Active Centers in the Unexpected Domain Arrangement of Glutamate Synthase

Claudia Binda, R Bossi, Soichi Wakatsuki et al. · Structure · 2000 · 86 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +6