Paola Magnaghi

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death

Paola Magnaghi, Roberto D’Alessio, Barbara Valsasina et al. · Nature Chemical Biology · 2013 · 380 citations

Biochemistry, Medicine, Natural Sciences +10

Entrectinib, a Pan–TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications

Elena Ardini, Maria Menichincheri, Patrizia Banfi et al. · Molecular Cancer Therapeutics · 2016 · 308 citations · Full text

Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

Maria Menichincheri, Elena Ardini, Paola Magnaghi et al. · Journal of Medicinal Chemistry · 2016 · 294 citations · Full text

HIRA, a mammalian homologue of Saccharomyces cerevisiae transcriptional co-repressors, interacts with Pax3

Paola Magnaghi, Catherine Roberts, Stéphanie Lorain et al. · Nature Genetics · 1998 · 167 citations

Transcriptional Co-repressors, Transcriptional Regulation, Genetics +8

Crystal Structures of Anaplastic Lymphoma Kinase in Complex with ATP Competitive Inhibitors

R Bossi, Maria Beatrice Saccardo, Elena Ardini et al. · Biochemistry · 2010 · 165 citations

Engineering, Molecular Biology, Anaplastic Lymphoma Kinase +18