Uwe Eberspächer

The Novel ATR Inhibitor BAY 1895344 Is Efficacious as Monotherapy and Combined with DNA Damage–Inducing or Repair–Compromising Therapies in Preclinical Cancer Models

Antje M. Wengner, Gerhard Siemeister, Ulrich Lücking et al. · Molecular Cancer Therapeutics · 2019 · 210 citations

Medicine, Molecular Biology, Oncology +17

Use of the Novel Plk1 Inhibitor ZK-Thiazolidinone to Elucidate Functions of Plk1 in Early and Late Stages of Mitosis

Anna Santamaría, Rüdiger Neef, Uwe Eberspächer et al. · Molecular Biology of the Cell · 2007 · 198 citations

Life Sciences, Cell Biology, Oncology +17

Affinity Map of Bromodomain Protein 4 (BRD4) Interactions with the Histone H4 Tail and the Small Molecule Inhibitor JQ1

Marie Jung, Martin Philpott, Susanne Müller et al. · Journal of Biological Chemistry · 2014 · 162 citations · Full text

Life Sciences, Chemical Biology, Molecular Biology +15

Damage Incorporated: Discovery of the Potent, Highly Selective, Orally Available ATR Inhibitor BAY 1895344 with Favorable Pharmacokinetic Properties and Promising Efficacy in Monotherapy and in Combination Treatments in Preclinical Tumor Models

Ulrich Lücking, Lars Wortmann, Antje M. Wengner et al. · Journal of Medicinal Chemistry · 2020 · 71 citations · Full text

Medicine, Medicinal Chemistry, Oncology +13

Inhibition of acrosin by protein C inhibitor and localization of protein C inhibitor to spermatozoa

X. Long Zheng, Margarethe Geiger, Sonja Ecke et al. · American Journal of Physiology-Cell Physiology · 1994 · 63 citations

Life Sciences, Biochemistry, Molecular Biology +15