Marina Fasolini

Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

Maria Menichincheri, Elena Ardini, Paola Magnaghi et al. · Journal of Medicinal Chemistry · 2016 · 298 citations · Full text

Medicine, Oncology, Pharmacology +17

<i>P</i>₀‐<i>Cre</i> Transgenic Mice for Inactivation of Adhesion Molecules in Schwann Cells

M. Laura Feltri, Maurizio D’Antonio, Stefano C. Previtali et al. · Annals of the New York Academy of Sciences · 1999 · 210 citations

Life Sciences, Genetics, Neuroscience +17

Inhibition of protein–protein interactions: The discovery of druglike β‐catenin inhibitors by combining virtual and biophysical screening

Jean‐Yves Trosset, Claudio Dalvit, Stefan Knapp et al. · Proteins Structure Function and Bioinformatics · 2006 · 181 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1<i>H</i>-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy

Gianluca Papeo, Helena Posteri, Daniela Borghi et al. · Journal of Medicinal Chemistry · 2015 · 143 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Tetramerization Dynamics of C-terminal Domain Underlies Isoform-specific cAMP Gating in Hyperpolarization-activated Cyclic Nucleotide-gated Channels

Marco Lolicato, Marco Nardini, Sabrina Gazzarrini et al. · Journal of Biological Chemistry · 2011 · 129 citations · Full text

Life Sciences, Biochemistry, Biophysics +13