Francesco Fiorentini

Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

Maria Menichincheri, Elena Ardini, Paola Magnaghi et al. · Journal of Medicinal Chemistry · 2016 · 298 citations · Full text

Medicine, Oncology, Pharmacology +17

A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity

Alessia Montagnoli, Barbara Valsasina, Valter Croci et al. · Nature Chemical Biology · 2008 · 215 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

Preclinical Studies in the mdx Mouse Model of Duchenne Muscular Dystrophy with the Histone Deacetylase Inhibitor Givinostat

Silvia Consalvi, Chiara Mozzetta, P. Bettica et al. · Molecular Medicine · 2013 · 165 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 1. Lead Finding

Paolo Pevarello, Maria Gabriella Brasca, Raffaella Amici et al. · Journal of Medicinal Chemistry · 2004 · 161 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Identification of <i>N</i>,1,4,4-Tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1<i>H</i>-pyrazolo[4,3-<i>h</i>]quinazoline-3-carboxamide (PHA-848125), a Potent, Orally Available Cyclin Dependent Kinase Inhibitor

Maria Gabriella Brasca, Nadia Amboldi, Dario Ballinari et al. · Journal of Medicinal Chemistry · 2009 · 128 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17