Concepedia

Decreased levels of proteasome activity and proteasome expression in aging spinal cord

Jeffrey N. Keller, Fengfa Huang, William R. Markesbery

Neuroscience · 2000 · 297 citations · 40 references

DOI

Concepts

References

40

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

Kenneth L. Rock, Colette F. Gramm, Lisa Rothstein et al. · Cell · 1994 · 2.5K citations

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Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

Gabriel Fenteany, Robert F. Standaert, William S. Lane et al. · Science · 1995 · 1.6K citations

, , +15

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease.

Charles D. Smith, John M. Carney, Pamela Starke‐Reed et al. · Proceedings of the National Academy of Sciences · 1991 · 1.3K citations

, , +17

Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction

Jeffrey N. Keller, Mark S. Kindy, Fredrick W. Holtsberg et al. · Journal of Neuroscience · 1998 · 873 citations · Full text

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Degradation of oxidized proteins in mammalian cells

Tilman Grune, Thomas Reinheckel, Kelvin J.A. Davies · The FASEB Journal · 1997 · 831 citations

, , +17