Concepedia

Genome-wide Loss-of-Function Screen Reveals an Important Role for the Proteasome in HDAC Inhibitor-Induced Apoptosis

Susan Fotheringham, Mirjam T. Epping, Lindsay Stimson, Omar Khan, Victoria Wood, Francesco Pezzella, René Bernards, Nicholas B. La Thangue

Cancer Cell · 2009 · 137 citations · 15 references

DOIFull text

Open access

Concepts

References

15

Impairment of the Ubiquitin-Proteasome System by Protein Aggregation

Neil Bence, Roopal M. Sampat, Ron R. Kopito · Science · 2001 · 2.2K citations

, , +17

FDA Approval Summary: Vorinostat for Treatment of Advanced Primary Cutaneous T-Cell Lymphoma

Bhupinder Mann, John R. Johnson, Martin H. Cohen et al. · The Oncologist · 2007 · 1.4K citations · Full text

, , +14

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

Katrien Berns, E. Marielle Hijmans, Jasper Mullenders et al. · Nature Cell Biology · 2004 · 1.1K citations · Full text

, , +14

Rad23 links DNA repair to the ubiquitin/proteasome pathway

Cherylene Schauber, Li Chen, Prasad Tongaonkar et al. · Nature · 1998 · 455 citations

, , +11

Proteins containing the UBA domain are able to bind to multi-ubiquitin chains

Caroline R.M. Wilkinson, Michael Seeger, Rasmus Hartmann‐Petersen et al. · Nature Cell Biology · 2001 · 407 citations

, , +11