The Human Tumor Antigen PRAME Is a Dominant Repressor of Retinoic Acid Receptor Signaling

Mirjam T. Epping, Liming Wang, Michael J. Edel, +3

Cell

Signal TransductionSignaling PathwayCell RegulationRetinoic Acid ReceptorMedicine +7

A transcriptional response to Wnt protein in human embryonic carcinoma cells

Jennifer Willert, Mirjam T. Epping, Jonathan R. Pollack, +2

BMC Developmental Biology

Tumor BiologyTranscriptional RegulationDevelopmental BiologySignaling PathwayMedicine +6

Apoptosis: target of cancer therapy.

Carlos Gil Ferreira, Mirjam T. Epping, Frank A.E. Kruyt, +1

PubMed

Cancer TherapyTumor Cell ApoptosisChemoprevention StrategyApoptosis-triggering ApproachesMedicine +12

ZNF423 Is Critically Required for Retinoic Acid-Induced Differentiation and Is a Marker of Neuroblastoma Outcome

Sidong Huang, Jamila Laoukili, Mirjam T. Epping, +10

Cancer Cell

Neuro-oncologyMolecular NeuroscienceRetinoic Acid-induced DifferentiationNeuroprotectionNeurology +4

A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer

Andrea Lunardi, Ugo Ala, Mirjam T. Epping, +18

Nature Genetics

Potential TherapiesUrologyGenitourinary CancerMedicineAndrogen Deprivation Resistance +5

Genome-wide Loss-of-Function Screen Reveals an Important Role for the Proteasome in HDAC Inhibitor-Induced Apoptosis

Susan Fotheringham, Mirjam T. Epping, Lindsay Stimson, +5

Cancer Cell

Important RoleProtein FunctionMedicineNatural SciencesApoptosis +7

TSPYL5 suppresses p53 levels and function by physical interaction with USP7

Mirjam T. Epping, Lars A.T. Meijer, Oscar Krijgsman, +3

Nature Cell Biology

MedicineMolecular BiologyPhysical InteractionTumor SuppressorP53 Levels +3

PRAME expression and clinical outcome of breast cancer

Mirjam T. Epping, A.A.M. Hart, Annuska M. Glas, +2

British Journal of Cancer

Vulnerabilities of <i>PTEN</i> – <i>TP53</i> -Deficient Prostate Cancers to Compound PARP–PI3K Inhibition

Enrique González‐Billalabeitia, Nina Seitzer, Su Jung Song, +17

Cancer Discovery

The preferentially expressed antigen in melanoma (PRAME) inhibits myeloid differentiation in normal hematopoietic and leukemic progenitor cells

Vivian G. Oehler, Katherine A. Guthrie, Carrie L. Cummings, +11

Blood