Concepedia

Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice

Bernd Kinzel, Monika Pikiolek, Vanessa Orsini, Joëlle Sprunger, Andrea Isken, Svenja Zietzling, Magali Desplanches, Valérie Dubost, Daniel Breustedt, Reginald Valdez,

Developmental Biology · 2014 · 97 citations · 24 references

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Identification of stem cells in small intestine and colon by marker gene Lgr5

Nick Barker, Johan H. van Es, Jeroen Kuipers et al. · Nature · 2007 · 5.7K citations

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Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

Wim de Lau, Nick Barker, Teck Yew Low et al. · Nature · 2011 · 1.3K citations

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The Hippo–YAP pathway in organ size control and tumorigenesis: an updated version

Bin Zhao, Li Li, Qun‐Ying Lei et al. · Genes & Development · 2010 · 1.1K citations · Full text

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ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

Huai-Xiang Hao, Yang Xie, Yue Zhang et al. · Nature · 2012 · 976 citations

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R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/β-catenin signaling

Kendra S. Carmon, Xing Gong, Qiushi Lin et al. · Proceedings of the National Academy of Sciences · 2011 · 857 citations · Full text

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