Concepedia

Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: Optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches

Boshi Huang, Cuicui Li, Wen‐Ming Chen, Tao Liu, Mingyan Yu, Lu Fu, Yueyue Sun, Huiqing Liu, Erik De Clercq, Christophe Pannecouque,

European Journal of Medicinal Chemistry · 2015 · 90 citations · 25 references

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The Protein Data Bank

Helen M. Berman · Nucleic Acids Research · 2000 · 39.8K citations

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Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

Rudi Pauwels, Jan Balzarini, Masanori Baba et al. · Journal of Virological Methods · 1988 · 1.6K citations

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Molecular obesity, potency and other addictions in drug discovery

Michael M. Hann · MedChemComm · 2011 · 354 citations

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Tetrazolium-based colorimetric assay for the detection of HIV replication inhibitors: revisited 20 years later

Christophe Pannecouque, Dirk Daelemans, Erik De Clercq · Nature Protocols · 2008 · 349 citations

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Crystal Structures of HIV-1 Reverse Transcriptase with Etravirine (TMC125) and Rilpivirine (TMC278): Implications for Drug Design

E.B. Lansdon, Katherine M. Brendza, Magdeleine Hung et al. · Journal of Medicinal Chemistry · 2010 · 226 citations

, , +17