Mingyan Yu

Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: Optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches

Boshi Huang, Cuicui Li, Wen‐Ming Chen et al. · European Journal of Medicinal Chemistry · 2015 · 90 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +15

Identification of a small-molecule Tim-3 inhibitor to potentiate T cell–mediated antitumor immunotherapy in preclinical mouse models

Shuaiya Ma, Ye Tian, Jiali Peng et al. · Science Translational Medicine · 2023 · 52 citations

Life Sciences, Immunology, Oncology +17

Increased Siglec-9/Siglec-9L interactions on NK cells predict poor HCC prognosis and present a targetable checkpoint for immunotherapy

Rong Xiao, Ye Tian, Jiwei Zhang et al. · Journal of Hepatology · 2024 · 35 citations

Life Sciences, Immunology, Oncology +12

Synthesis and biological evaluation of novel 2-(substituted phenylaminocarbonylmethylthio)-6-(2,6-dichlorobenzyl)-pyrimidin-4(3H)-ones as potent HIV-1 NNRTIs

Mingyan Yu, Xinyong Liu, Zhenyu Li et al. · Bioorganic & Medicinal Chemistry · 2009 · 25 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Synthesis and Biological Evaluation of 6‐Substituted 5‐Alkyl‐2‐(phenylaminocarbonylmethylthio)pyrimidin‐4(3<i>H</i>)‐ones as Potent HIV‐1 NNRTIs

Mingyan Yu, Zhenyu Li, Shuai Liu et al. · ChemMedChem · 2011 · 15 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17