E.B. Lansdon

Crystal Structures of HIV-1 Reverse Transcriptase with Etravirine (TMC125) and Rilpivirine (TMC278): Implications for Drug Design

E.B. Lansdon, Katherine M. Brendza, Magdeleine Hung et al. · Journal of Medicinal Chemistry · 2010 · 224 citations

Biomolecular Structure Prediction, Molecular Biology, Antiviral Drug +16

Discovery of GS-9973, a Selective and Orally Efficacious Inhibitor of Spleen Tyrosine Kinase

Kevin Currie, Jeffrey E. Kropf, Tony Lee et al. · Journal of Medicinal Chemistry · 2014 · 167 citations · Full text

Orally Efficacious Inhibitor, Drug Target, Immunology +18

New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action

Manuel Tsiang, G.S. Jones, Anita Niedziela‐Majka et al. · Journal of Biological Chemistry · 2012 · 158 citations · Full text

Hiv-1 Integrase, Medicine, Human Retrovirus +10

ASK1 contributes to fibrosis and dysfunction in models of kidney disease

John T. Liles, Britton K. Corkey, Gregory T. Notte et al. · Journal of Clinical Investigation · 2018 · 137 citations · Full text

RNase H Active Site Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Design, Biochemical Activity, and Structural Information

Thorsten Kirschberg, M. Balakrishnan, Neil Squires et al. · Journal of Medicinal Chemistry · 2009 · 96 citations · Full text

Structural Information, Bioorganic Chemistry, Molecular Biology +19