Kevin Currie

Specific Btk inhibition suppresses B cell– and myeloid cell–mediated arthritis

Julie A. Di Paolo, Tao Huang, Mercedesz Balázs et al. · Nature Chemical Biology · 2010 · 328 citations · Full text

Inflammation, Rheumatology, Rheumatoid Disorder +11

Discovery of GS-9973, a Selective and Orally Efficacious Inhibitor of Spleen Tyrosine Kinase

Kevin Currie, Jeffrey E. Kropf, Tony Lee et al. · Journal of Medicinal Chemistry · 2014 · 167 citations · Full text

Orally Efficacious Inhibitor, Drug Target, Immunology +18

Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton’s Tyrosine Kinase Inhibitor

Lichuan Liu, Jason Halladay, Young G. Shin et al. · Drug Metabolism and Disposition · 2011 · 73 citations

Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell–associated damage in IFNα-driven lupus nephritis

Arna Katewa, Yugang Wang, Jason A. Hackney et al. · JCI Insight · 2017 · 72 citations · Full text

A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor

Russell T. Burke, Sarah Meadows, Marc Loriaux et al. · Oncotarget · 2014 · 65 citations · Full text