Marc Loriaux

Functional genomic landscape of acute myeloid leukaemia

Jeffrey Tyner, Cristina E. Tognon, Daniel Bottomly et al. · Nature · 2018 · 1.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance

Thomas O’Hare, William C. Shakespeare, Xiaotian Zhu et al. · Cancer Cell · 2009 · 1.2K citations · Full text

Medicine, Oncology, Pharmacology +9

Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma

David Clark, Saravana M. Dhanasekaran, Francesca Petralia et al. · Cell · 2019 · 774 citations · Full text

Medicine, Oncology, Pathobiology +17

Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity

Amie S. Corbin, Anupriya Agarwal, Marc Loriaux et al. · Journal of Clinical Investigation · 2010 · 763 citations

Medicine, Cell Biology, Oncology +17

CAL-101, a p110δ selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability

Brian J. Lannutti, Sarah Meadows, Sarah E. M. Herman et al. · Blood · 2010 · 718 citations · Full text

Medicine, Oncology, Pharmacology +11