Inducible costimulator facilitates T-dependent B cell activation by augmenting IL-4 translation

Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

Masamichi Muramatsu, Kazuo Kinoshita, Sidonia Fagarasan et al. · Cell · 2000 · 3.4K citations

Natural Sciences, Genetics, Rna Biology +7

Activation-Induced Cytidine Deaminase (AID) Deficiency Causes the Autosomal Recessive Form of the Hyper-IgM Syndrome (HIGM2)

Patrick Revy, Taro Muto, Yves Lévy et al. · Cell · 2000 · 1.6K citations · Full text

Mendelian Disorder, Autoimmune Disease, Genetic Disorder +8

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

Andreas Hutloff, Anna‐Maria Dittrich, Katja C. Beier et al. · Nature · 1999 · 1.5K citations

Signal Transduction, Autoimmune Disease, Adaptive Immune System +10

Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages

Roza Nurieva, Yeonseok Chung, Daehee Hwang et al. · Immunity · 2008 · 1.2K citations · Full text

Autoimmune Disease, Cell Lineages, Adaptive Immune System +6

Cytokine-secreting follicular T cells shape the antibody repertoire

R. Lee Reinhardt, Hong-Erh Liang, Richard M. Locksley · Nature Immunology · 2009 · 799 citations · Full text

Autoimmune Disease, Immunology, Antigen Processing +6