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Discovery of a novel small molecule binding site of human survivin

Michael Wendt, Chaohong Sun, Aaron Kunzer, Daryl R. Sauer, Kathy Sarris, Ethan Hoff, Liping Yu, David G. Nettesheim, Jun Chen, Sha Jin,

Bioorganic & Medicinal Chemistry Letters · 2007 · 81 citations · 40 references

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40

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

Grazia Ambrosini, Colette Adida, Dario C. Altieri · Nature Medicine · 1997 · 3.2K citations

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IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs.

Ingo Tamm, Yi Wang, Edward A. Sausville et al. · PubMed · 1998 · 1.3K citations

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Structural basis for phosphoserine-proline recognition by group IV WW domains.

Mark A. Verdecia, M.E. Bowman, Kun Ping Lu et al. · Nature Structural Biology · 2000 · 697 citations

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Convergent Solutions to Binding at a Protein-Protein Interface

Warren L. DeLano, Mark Ultsch, Abraham M. de et al. · Science · 2000 · 682 citations

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An Anti-apoptotic Protein Human Survivin Is a Direct Inhibitor of Caspase-3 and -7

Sejeong Shin, Byungje Sung, Yong‐Soon Cho et al. · Biochemistry · 2001 · 678 citations

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