David G. Nettesheim

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

Tilman Oltersdorf, Steven W. Elmore, Alexander R. Shoemaker et al. · Nature · 2005 · 3.4K citations

Tumor Biology, Bcl-2 Family Proteins, Medicine +9

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

Steven W. Muchmore, Michael Sattler, Heng Liang et al. · Nature · 1996 · 1.5K citations

Nmr Structure, Apoptosis, Cell Death +7

Structure of Bcl-x _L -Bak Peptide Complex: Recognition Between Regulators of Apoptosis

Michael Sattler, Heng Liang, David G. Nettesheim et al. · Science · 1997 · 1.5K citations

Protein Function, Signal Transduction, Heterodimer Formation +15

Solution structure of the antiapoptotic protein bcl-2

Andrew M. Petros, A Medek, David G. Nettesheim et al. · Proceedings of the National Academy of Sciences · 2001 · 447 citations · Full text

Rationale for Bcl‐X_L/Bad peptide complex formation from structure, mutagenesis, and biophysical studies

Andrew M. Petros, David G. Nettesheim, Yi Wang et al. · Protein Science · 2000 · 388 citations · Full text