Rhodium-catalyzed diastereoselective 1,2-addition of arylboronic acids to chiral trifluoroethyl imine

The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K

Jacques Yves Gauthier, Nathalie Chauret, Wanda Cromlish et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 473 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

<i>N</i>-Boc-<scp>l</scp>-Valine-Connected Amidomonophosphane Rhodium(I) Catalyst for Asymmetric Arylation of <i>N-</i>Tosylarylimines with Arylboroxines

Masami Kuriyama, Takahiro Soeta, Xinyu Hao et al. · Journal of the American Chemical Society · 2004 · 219 citations

Natural Sciences, Chemistry, Medicinal Chemistry +16

Diastereoselective and Enantioselective Rh(I)-Catalyzed Additions of Arylboronic Acids to <i>N</i>-<i>tert</i>-Butanesulfinyl and <i>N</i>-Diphenylphosphinoyl Aldimines

Daniel J. Weix, Yili Shi, Jonathan A. Ellman · Journal of the American Chemical Society · 2005 · 192 citations

Natural Sciences, Chemistry, Catalysis +8

Trifluoroethylamines as amide isosteres in inhibitors of cathepsin K

W. Cameron Black, Christopher I. Bayly, Dana Davis et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 140 citations

Life Sciences, Chemistry, Medicinal Chemistry +14

Difluoroethylamines as an amide isostere in inhibitors of cathepsin K

Élise Isabel, Christophe Mellon, Michael J. Boyd et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 111 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +12