Concepedia

The role of indoleamine 2,3-dioxygenase (IDO) in immune tolerance: Focus on macrophage polarization of THP-1 cells

Xianfeng Wang, Hongsheng Wang, Hao Wang, Fan Zhang, Kefang Wang, Qiang Guo, Ge Zhang, Shaohui Cai, Jun Du

Cellular Immunology · 2014 · 220 citations · 23 references

DOI

Concepts

References

23

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

Catherine Uyttenhove, Luc Pilotte, Ivan Théate et al. · Nature Medicine · 2003 · 2.3K citations

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IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

Thomas Krausgruber, Katrina Blazek, Tim Smallie et al. · Nature Immunology · 2011 · 1.3K citations · Full text

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Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy

Alexander J. Muller, James B. DuHadaway, Preston S. Donover et al. · Nature Medicine · 2005 · 1.1K citations

, , +16

Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes

David H. Munn, Madhav Sharma, De‐Yan Hou et al. · Journal of Clinical Investigation · 2004 · 846 citations · Full text

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Human MSC Suppression Correlates With Cytokine Induction of Indoleamine 2,3-Dioxygenase and Bystander M2 Macrophage Differentiation

Moïra François, Raphaëlle Romieu‐Mourez, Mengyang Li et al. · Molecular Therapy · 2011 · 710 citations · Full text

, , +16