James B. DuHadaway

Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy

Alexander J. Muller, James B. DuHadaway, Preston S. Donover et al. · Nature Medicine · 2005 · 1.1K citations

Medicine, Oncology, Pharmacology +16

Inhibition of Indoleamine 2,3-Dioxygenase in Dendritic Cells by Stereoisomers of 1-Methyl-Tryptophan Correlates with Antitumor Responses

De-Yan Hou, Alexander J. Muller, Madhav Sharma et al. · Cancer Research · 2007 · 583 citations

Life Sciences, Oncology, Pharmacology +17

Novel Tryptophan Catabolic Enzyme IDO2 Is the Preferred Biochemical Target of the Antitumor Indoleamine 2,3-Dioxygenase Inhibitory Compound <scp>d</scp> -1-Methyl-Tryptophan

Richard Metz, James B. DuHadaway, Uma Kamasani et al. · Cancer Research · 2007 · 463 citations · Full text

Life Sciences, Immunology, Pharmacology +13

Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

Nozomi Takahashi, Linde Duprez, Sasker Grootjans et al. · Cell Death and Disease · 2012 · 445 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

Richard Metz, Sonja Rust, James B. DuHadaway et al. · OncoImmunology · 2012 · 377 citations · Full text

Life Sciences, Immunology, Oncology +17