<i>In vitro</i>cytotoxic and anticlastogenic activities of saxifragifolin B and cyclamin isolated from<i>Cyclamen persicum</i>and<i>Cyclamen libanoticum</i>

Abstract

This study showed the remarkable cytotoxic activity of saxifragifolin B, especially against breast adenocarcinoma and lung carcinoma and its chemoprotective activity against mitomycin C. Thus, saxifragifolin B could be suggested as a potential cytotoxic drug with a preventive effect against possible exposures to genotoxic agents.