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Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP

Min Lü, Hilde Breyssens, Victoria Salter, Shan Zhong, Ying Hu, Caroline Baer, Indrika Ratnayaka, Alex Sullivan, Nicholas R. Brown, Jane Endicott,

Cancer Cell · 2013 · 163 citations · 34 references

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34

Distinct Sets of Genetic Alterations in Melanoma

John A. Curtin, Jane Fridlyand, Toshiro Kageshita et al. · New England Journal of Medicine · 2005 · 2.7K citations · Full text

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ARF Promotes MDM2 Degradation and Stabilizes p53: ARF-INK4a Locus Deletion Impairs Both the Rb and p53 Tumor Suppression Pathways

Yanping Zhang, Yue Xiong, Wendell G. Yarbrough · Cell · 1998 · 1.6K citations · Full text

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Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis

Jesper V. Olsen, Michiel Vermeulen, Anna Santamaría et al. · Science Signaling · 2010 · 1.5K citations

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ASPP Proteins Specifically Stimulate the Apoptotic Function of p53

Yardena Samuels-Lev, Daniel O’Connor, Daniele Bergamaschi et al. · Molecular Cell · 2001 · 664 citations · Full text

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The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner

Eric W. Joseph, Christine A. Pratilas, Poulikos I. Poulikakos et al. · Proceedings of the National Academy of Sciences · 2010 · 447 citations · Full text

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