Nicholas R. Brown

A soluble CD4 protein selectively inhibits HIV replication and syncytium formation

Rebecca E. Hussey, Neil Richardson, Mark Kowalski et al. · Nature · 1988 · 425 citations

Viral Replication, Human Retrovirus, Syncytium Formation +10

CDK1 structures reveal conserved and unique features of the essential cell cycle CDK

Nicholas R. Brown, S. Korolchuk, Mathew P. Martin et al. · Nature Communications · 2015 · 249 citations · Full text

Effects of Phosphorylation of Threonine 160 on Cyclin-dependent Kinase 2 Structure and Activity

Nicholas R. Brown, M.E.M. Noble, Alison M. Lawrie et al. · Journal of Biological Chemistry · 1999 · 224 citations · Full text

Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP

Benjamin Stieglitz, Rohini R. Rana, Marios G. Koliopoulos et al. · Nature · 2013 · 208 citations · Full text

Protein Function, Ligase-specific Conjugation, Structural Bioinformatics +5

Phosphoprotein–Protein Interactions Revealed by the Crystal Structure of Kinase-Associated Phosphatase in Complex with PhosphoCDK2

Haiwei Song, Neil Hanlon, Nicholas R. Brown et al. · Molecular Cell · 2001 · 175 citations · Full text

Phosphoprotein–protein Interactions, Crystal Structure, Protein Function +10