TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

Mamta Tahiliani, Kian Peng Koh, Yinghua Shen et al. · Science · 2009 · 5.8K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

María E. Figueroa, Omar Abdel‐Wahab, Chao Lü et al. · Cancer Cell · 2010 · 2.7K citations · Full text

Medicine, Genetics, Hematology +17

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

Skirmantas Kriaučionis, Nathaniel Heintz · Science · 2009 · 2.7K citations

Life Sciences, Genetics, Molecular Biology +15

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

Shinsuke Ito, Ana C. D’Alessio, Olena Taranova et al. · Nature · 2010 · 2.5K citations

Life Sciences, Cell Biology, Molecular Biology +8

<i>DNMT3A</i> Mutations in Acute Myeloid Leukemia

Timothy J. Ley, Li Ding, Matthew J. Walter et al. · New England Journal of Medicine · 2010 · 2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17