Concepedia

Dipeptide isosteres. 2. Synthesis of hydroxyethylene dipeptide isostere diastereomers from a common γ-lactone intermediate. Preparation of renin and HIV-1 protease inhibitor transition state mimics.

William R. Baker, John K. Pratt

Tetrahedron · 1993 · 34 citations · 40 references

DOI

Concepts

References

40

A greatly improved procedure for ruthenium tetroxide catalyzed oxidations of organic compounds

Per H. J. Carlsen, Tsutomu Katsuki, Victor S. Martı́n et al. · The Journal of Organic Chemistry · 1981 · 1.6K citations

, , +7

L-687,908, a potent hydroxyethylene containing HIV protease inhibitor

Joseph P. Vacca, James P. Guare, S. J. DESOLMS et al. · Journal of Medicinal Chemistry · 1991 · 124 citations · Full text

, , +9

A stereocontrolled synthesis of hydroxyethylene dipeptide isosteres using novel, chiral aminoalkyl epoxides and .gamma.-(aminoalkyl)-.gamma.-lactones

B. Evans, Kenneth E. Rittle, Carl F. Homnick et al. · The Journal of Organic Chemistry · 1985 · 118 citations

, , +8

Nickel-catalyzed cross-coupling of silyl enol ethers with grignard reagents. Regio- and stereocontrolled synthesis of olefins

Tamio Hayashi, Yoshio Katsuro, Makoto Kumada · Tetrahedron Letters · 1980 · 112 citations

, , +10

Synthesis and biological activity of some transition-state inhibitors of human renin

Walter Fuhrer, Vittorio Rasetti, H. Rüeger et al. · Journal of Medicinal Chemistry · 1988 · 111 citations · Full text

, , +13