James P. Guare

L-735,524: The Design of a Potent and Orally Bioavailable HIV Protease Inhibitor

Bruce D. Dorsey, Rhonda B. Levin, Stacey L. McDaniel et al. · Journal of Medicinal Chemistry · 1994 · 408 citations · Full text

A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

Daria J. Hazuda, Neville J. Anthony, Robert Gomez et al. · Proceedings of the National Academy of Sciences · 2004 · 332 citations · Full text

Hiv-1 Integrase, Immunology, Cell Culture +17

Integrase Inhibitors and Cellular Immunity Suppress Retroviral Replication in Rhesus Macaques

Daria J. Hazuda, Steven D. Young, James P. Guare et al. · Science · 2004 · 283 citations · Full text

Viral Replication, Siv Integrase, Immunology +19

Design and Synthesis of 8-Hydroxy-[1,6]Naphthyridines as Novel Inhibitors of HIV-1 Integrase in Vitro and in Infected Cells

Linghang Zhuang, John Wai, Mark W. Embrey et al. · Journal of Medicinal Chemistry · 2003 · 266 citations · Full text

Hiv-1 Integrase, Biochemistry, Medicine +14

4-Aryl-2,4-dioxobutanoic Acid Inhibitors of HIV-1 Integrase and Viral Replication in Cells

John Wai, Melissa S. Egbertson, Linda S. Payne et al. · Journal of Medicinal Chemistry · 2000 · 187 citations · Full text

Hiv-1 Integrase, Viral Replication, Immunology +17