James P. Guare - Concepedia

Concepedia

Author

James P. Guare

United States Military Academy

Also Known As

J. GUARE, J. P. GUARE, J. P. Guare, J. P. JUN. GUARE, J.P. Guare, James Guare, James P Guare, James P. Guare, James P. Guare,

46

Publications

2.2K

Citations

17

H-Index

42

Concepts

All Affiliations

United States Military Academy Merck & Co., Inc., Rahway, NJ, USA (United States)

JP

About

James P. Guare is an author at United States Military Academy specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	14	18	1.7K
2	Biochemistry	12	13	632
3	Natural Sciences	9	9	347
4	Engineering	1	1	10
5	Biomolecular Engineering	1	1	332

James P. Guare

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23

Publications

2.2K

Citations

17

H-Index

	Year	Citations
L-735,524: The Design of a Potent and Orally Bioavailable HIV Protease Inhibitor Bruce D. Dorsey, Rhonda B. Levin, Stacey L. McDaniel, Journal of Medicinal Chemistry	1994	408
A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase Daria J. Hazuda, Neville J. Anthony, Robert Gomez, Proceedings of the National Academy of Sciences Hiv-1 IntegraseImmunologyCell CulturePharmacotherapyAntiviral Drug	2004	332
Integrase Inhibitors and Cellular Immunity Suppress Retroviral Replication in Rhesus Macaques Daria J. Hazuda, Steven D. Young, James P. Guare, Science Viral ReplicationSiv IntegraseImmunologyAntiviral DrugImmunotherapy	2004	283
Design and Synthesis of 8-Hydroxy-[1,6]Naphthyridines as Novel Inhibitors of HIV-1 Integrase in Vitro and in Infected Cells Linghang Zhuang, John Wai, Mark W. Embrey, Journal of Medicinal Chemistry Hiv-1 IntegraseBiochemistryMedicineImmunologyAntiviral Drug Development	2003	266
4-Aryl-2,4-dioxobutanoic Acid Inhibitors of HIV-1 Integrase and Viral Replication in Cells John Wai, Melissa S. Egbertson, Linda S. Payne, Journal of Medicinal Chemistry Hiv-1 IntegraseViral ReplicationImmunologyAltmetric Attention ScoreCell Culture	2000	187
L-687,908, a potent hydroxyethylene containing HIV protease inhibitor Joseph P. Vacca, James P. Guare, S. J. DESOLMS, Journal of Medicinal Chemistry Pharmaceutical ScienceAltmetric Attention ScorePharmacotherapyAntiviral DrugPharmaceutical Chemistry	1991	124
PD-1 Blockade in Rhesus Macaques: Impact on Chronic Infection and Prophylactic Vaccination Adam C. Finnefrock, Aimin Tang, Fengsheng Li, The Journal of Immunology Pd-1 BlockadeNaive MacaquesAdaptive Immune SystemViral ImmunityImmunology	2009	114
Benzocycloalkyl amines as novel C-termini for HIV protease inhibitors Terry A. Lyle, Catherine M. Wiscount, James P. Guare, Journal of Medicinal Chemistry Hiv Protease InhibitorsAltmetric Attention ScorePharmacotherapyAntiviral DrugPharmaceutical Chemistry	1991	97
Development of Orally Active Oxytocin Antagonists: Studies on 1-(1-{4-[1-(2-Methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl}piperidin-4-yl)-1,4-dihydrobenz[<i>d</i>][1,3]oxazin-2-one (L-372,662) and Related Pyridines Ian M. Bell, Jill M. Erb, Roger Freidinger, Journal of Medicinal Chemistry PharmacotherapyOrally Active OxytocinExperimental PharmacologyPharmaceutical ChemistryOxytocin Antagonists	1998	60
A series of 5-aminosubstituted 4-fluorobenzyl-8-hydroxy-[1,6]naphthyridine-7-carboxamide HIV-1 integrase inhibitors James P. Guare, John Wai, Robert Gomez, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryBioorganic ChemistryMedicineNatural SciencesAntiviral Drug Development	2006	50

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