S. J. DESOLMS

Selective Inhibition of <i>ras</i> -Dependent Transformation by a Farnesyltransferase Inhibitor

Nancy E. Kohl, Scott D. Mosser, S. J. DESOLMS et al. · Science · 1993 · 582 citations

Medicine, Oncology, Pharmacology +13

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

Nancy E. Kohl, Charles A. Omer, Michael W. Conner et al. · Nature Medicine · 1995 · 539 citations

Medicine, Cancer Biology, Oncology +11

Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice.

Nancy E. Kohl, Francine R. Wilson, S D Mosser et al. · Proceedings of the National Academy of Sciences · 1994 · 285 citations

Medicine, Oncology, Pharmacology +13

Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.

Robert B. Lobell, CharlesA. Omer, Marc Abrams et al. · PubMed · 2001 · 239 citations

Medicine, Oncology, Pharmacology +16

Farnesyltransferase Inhibition Causes Morphological Reversion of <i>ras</i> -Transformed Cells by a Complex Mechanism That Involves Regulation of the Actin Cytoskeleton

George C. Prendergast, Joseph P. Da Vide, S. J. DESOLMS et al. · Molecular and Cellular Biology · 1994 · 194 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17