Marc Abrams

Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.

Robert B. Lobell, CharlesA. Omer, Marc Abrams et al. · PubMed · 2001 · 239 citations

Medicine, Oncology, Pharmacology +16

Evaluation of Efficacy, Biodistribution, and Inflammation for a Potent siRNA Nanoparticle: Effect of Dexamethasone Co-treatment

Marc Abrams, Martin L. Koser, Jessica Seitzer et al. · Molecular Therapy · 2009 · 208 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

Kinesin Spindle Protein (KSP) Inhibitors. 9. Discovery of (2<i>S</i>)-4-(2,5-Difluorophenyl)-<i>N</i>-[(3<i>R</i>,4<i>S</i>)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-<i>N</i>-methyl-2-phenyl-2,5-dihydro-1<i>H</i>-pyrrole-1-carboxamide (MK-0731) for the Treatment of Taxane-Refractory Cancer

Christopher D. Cox, Paul J. Coleman, Michael J. Breslin et al. · Journal of Medicinal Chemistry · 2008 · 156 citations · Full text

Medicine, Oncology, Pharmacology +13

Hepatocyte‐Specific β‐Catenin Deletion During Severe Liver Injury Provokes Cholangiocytes to Differentiate Into Hepatocytes

Jacquelyn O. Russell, Wei‐Yu Lu, Marc Abrams et al. · Hepatology · 2018 · 143 citations · Full text

Medicine, Cell Biology, Cell Signaling +14

Phosphorylation of Linker Histone H1 Regulates Gene Expression In Vivo by Mimicking H1 Removal

Yali Dou, Craig A. Mizzen, Marc Abrams et al. · Molecular Cell · 1999 · 138 citations · Full text

Life Sciences, Genetics, Molecular Biology +11