αβ T Cell Development Is Abolished in Mice Lacking Both Lck and Fyn Protein Tyrosine Kinases

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

Yoichi Shinkai · Cell · 1992 · 2.6K citations

Life Sciences, Genetics, Immunology +14

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice.

Jacques J. Peschon, Philip Morrissey, Kenneth H. Grabstein et al. · The Journal of Experimental Medicine · 1994 · 1.6K citations · Full text

Life Sciences, Genetics, Immunology +17

Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages

Peter Mombaerts, Alan R. Clarke, Michael A. Rudnicki et al. · Nature · 1992 · 1.1K citations

Life Sciences, Genetics, Immunology +16

Profound block in thymocyte development in mice lacking p56lck

Thierry Jo Molina, Kenji Kishihara, David P. Siderovski et al. · Nature · 1992 · 966 citations

Life Sciences, Genetics, Molecular Biology +9

A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression

Dale I. Godfrey, Jacqueline Kennedy, Toshio Suda et al. · The Journal of Immunology · 1993 · 836 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +17