Concepedia

Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo

Hiroyuki Niida, Kazuhiro Murata, Midori Shimada, Kumiko Ogawa, Kumiko Ohta, Kyoko Suzuki, Hidetsugu Fujigaki, Aik Kia Khaw, Birendranath Banerjee, M. Prakash Hande,

The EMBO Journal · 2010 · 59 citations · 53 references

DOI

Concepts

References

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Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5.1K citations · Full text

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

Martin Scheffner, Bruce A. Werness, Jon M. Huibregtse et al. · Cell · 1990 · 4K citations

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A DNA damage checkpoint response in telomere-initiated senescence

Fabrizio d’Adda di Fagagna, Philip M. Reaper, Lorena Clay-Farrace et al. · Nature · 2003 · 2.8K citations

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

Jiřina Bártková, Zuzana Hořejšı́, Karen Koed et al. · Nature · 2005 · 2.7K citations

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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

Vassilis G. Gorgoulis, Leandros-Vassilios Vassiliou, Panagiotis Karakaidos et al. · Nature · 2005 · 2K citations

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