Vassilis G. Gorgoulis

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

Vassilis G. Gorgoulis, Leandros-Vassilios Vassiliou, Panagiotis Karakaidos et al. · Nature · 2005 · 2K citations

Dna Damage Checkpoint, Genome Instability, Dna Damage +11

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

Jiřina Bártková, Nousin Rezaei, Michalis Liontos et al. · Nature · 2006 · 1.9K citations

Oncogene-induced Senescence, Chromatin, Genome Instability +11

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

Yentram Huyen, Omar Zgheib, Richard A. DiTullio et al. · Nature · 2004 · 867 citations

Histone Modifications, Chromatin, Genome Instability +13

Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246

Tomer Cooks, Ioannis S. Pateras, Lisa M. Jenkins et al. · Nature Communications · 2018 · 471 citations · Full text

Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

Tomer Cooks, Ioannis S. Pateras, Ohad Tarcic et al. · Cancer Cell · 2013 · 457 citations · Full text