Richard A. DiTullio

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

Vassilis G. Gorgoulis, Leandros-Vassilios Vassiliou, Panagiotis Karakaidos et al. · Nature · 2005 · 2K citations

Dna Damage Checkpoint, Genome Instability, Dna Damage +11

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

Yentram Huyen, Omar Zgheib, Richard A. DiTullio et al. · Nature · 2004 · 867 citations

Histone Modifications, Chromatin, Genome Instability +13

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

Richard A. DiTullio, Tamara A. Mochan, Monica Venere et al. · Nature Cell Biology · 2002 · 401 citations

Oncology, Medicine, Cell Death +10

53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage.

Tamara A. Mochan, Monica Venere, Richard A. DiTullio et al. · PubMed · 2003 · 193 citations

Chromatin, Genome Instability, Dna Damage +11

53BP1, an activator of ATM in response to DNA damage

Tamara A. Mochan, Monica Venere, Richard A. DiTullio et al. · DNA repair · 2004 · 152 citations

Chromatin, Genome Instability, Dna Damage +7