Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

Vassilis G. Gorgoulis, Leandros-Vassilios Vassiliou, Panagiotis Karakaidos, +12

Nature

Dna Damage CheckpointGenome InstabilityDna DamageMedicinePathology +9

Embryonic stem cell–specific microRNAs promote induced pluripotency

Robert L. Judson, Joshua Babiarz, Monica Venere, +1

Nature Biotechnology

Induced Pluripotent Stem CellDevelopmental BiologyMedicineStem Cell ResearchMicrorna Detection +4

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

Richard A. DiTullio, Tamara A. Mochan, Monica Venere, +4

Nature Cell Biology

OncologyMedicineCell DeathCancer Cell BiologyHuman Cancer +8

SCFβTrCP-Mediated Degradation of Claspin Regulates Recovery from the DNA Replication Checkpoint Response

Angelo Peschiaroli, N. Valerio Dorrello, Daniele Guardavaccaro, +4

Molecular Cell

ChromatinGenome InstabilityTranscriptional RegulationProtein FunctionClaspin Regulates Recovery +9

53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage.

Tamara A. Mochan, Monica Venere, Richard A. DiTullio, +1

PubMed

ChromatinGenome InstabilityDna DamageGeneticsMutant Nbs1 +9

The mitotic kinesin KIF11 is a driver of invasion, proliferation, and self-renewal in glioblastoma

Monica Venere, Craig Horbinski, James F. Crish, +12

Science Translational Medicine

Neuro-oncologyGliomaMitotic Kinesin Kif11MedicineCancer Cell Biology +11

Therapeutic targeting of constitutive PARP activation compromises stem cell phenotype and survival of glioblastoma-initiating cells

Monica Venere, Petra Hamerlik, Qiulian Wu, +8

Cell Death and Differentiation

Neuro-oncologySignaling PathwayMedicineTherapeutic TargetingNeural Stem Cell +11

Laminin alpha 2 enables glioblastoma stem cell growth

Justin D. Lathia, Meizhang Li, Peter E. Hall, +21

Annals of Neurology

53BP1, an activator of ATM in response to DNA damage

Tamara A. Mochan, Monica Venere, Richard A. DiTullio, +1

DNA repair

ChromatinGenome InstabilityDna DamageNatural SciencesGenetics +5

Defective apoptosis and B‐cell lymphomas in mice with p53 point mutation at Ser 23

David MacPherson, Jungho Kim, Teresa S. Kim, +9

The EMBO Journal