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ISOFORM SELECTIVITY AND KINETICS OF MORPHINE 3- AND 6-GLUCURONIDATION BY HUMAN UDP-GLUCURONOSYLTRANSFERASES: EVIDENCE FOR ATYPICAL GLUCURONIDATION KINETICS BY UGT2B7

Andrew N. Stone, Peter I. Mackenzie, Aleksandra Galetin, J. Brian Houston, John O. Miners

Drug Metabolism and Disposition · 2003 · 203 citations · 13 references

DOI

References

13

Human UGT2B7 catalyzes morphine glucuronidation.

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In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model

J. Brian Houston, Kathryn E. Kenworthy · Drug Metabolism and Disposition · 2000 · 392 citations

The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268).

Birgit L. Coffman, Christopher D. King, Gladys R. Rios et al. · PubMed · 1998 · 326 citations

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Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3.

Mitchell D. Green, Christopher D. King, B. Mojarrabi et al. · PubMed · 1998 · 258 citations

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Multisite kinetic models for CYP3A4: simultaneous activation and inhibition of diazepam and testosterone metabolism.

Kathryn E. Kenworthy, Stephen E. Clarke, J. Andrews et al. · PubMed · 2001 · 160 citations

, , +16