Christopher D. King

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.

Lalitha Iyer, Christopher D. King, P. F. Whitington et al. · Journal of Clinical Investigation · 1998 · 677 citations · Full text

Aldo-keto Reductase, Chemoprevention Strategy, Genetics +23

Human UGT2B7 catalyzes morphine glucuronidation.

Birgit L. Coffman, Gladys R. Rios, Christopher D. King et al. · PubMed · 1997 · 426 citations

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +13

The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268).

Birgit L. Coffman, Christopher D. King, Gladys R. Rios et al. · PubMed · 1998 · 326 citations

Other Xenobiotics, Hk 293, Pharmacotherapy +17

Deficiency in endogenous modulation of prolonged heat pain in patients with Irritable Bowel Syndrome and Temporomandibular Disorder

Christopher D. King, Fong Wong, T. Currie et al. · Pain · 2009 · 285 citations

Pain Disorders, Pain Medicine, Neuropathic Pain +18

Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3.

Mitchell D. Green, Christopher D. King, B. Mojarrabi et al. · PubMed · 1998 · 258 citations

Bioorganic Chemistry, Aldo-keto Reductase, Other Xenobiotics +18